Sara M. Tolaney, MD, MPH, describes how in the past decade, there has been a shift in practice to allow for an adaptive approach based on a patient's response to preoperative therapy.
She cites the KATHERINE study as an example where data showed that use of T-DM1 in patients with residual invasive HER2-Positive breast cancer reduced recurrences by half. These data are a prime example that demonstrate how understanding a patient's response to therapy can lead to better outcomes.
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Cite this: Adapting Breast Cancer Treatment Based on Initial Response - Medscape - Apr 24, 2023.
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