Adapting Breast Cancer Treatment Based on Initial Response

Sara M. Tolaney, MD, MPH

Disclosures

April 24, 2023

Sara M. Tolaney, MD, MPH, describes how in the past decade, there has been a shift in practice to allow for an adaptive approach based on a patient's response to preoperative therapy.

She cites the KATHERINE study as an example where data showed that use of T-DM1 in patients with residual invasive HER2-Positive breast cancer reduced recurrences by half. These data are a prime example that demonstrate how understanding a patient's response to therapy can lead to better outcomes.

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